| Street Name | Description |
| A | LSD, amphetamine |
| Abandominiums | Abondoned row houses where drugs are used |
| Abe | $5 worth of drugs |
| AbeÂ’s cabe | $5 bill |
| Abolic | Veterinary Steroids |
| A-bomb | Marijuana cigarette with heroin or opium |
| A-boot | Under the influence of Drugs |
| Abyssinian tea | Khat |
| AC/DC | Codeine cough syrup |
| Acapulco gold | Marijuana from SW Mexico |
| Acapulco red | Marijuana |
| Ace | Marijuana cigarette, PCP |
| Acid | LSD |
| Acid freak | Heavy user of LSD |
| Acid head | User of LSD |
| Acido (Spanish) | Hallucinogens, LSD |
| Ad | PCP, drug addict |
| Adam | Ecstasy |
| Adam | XPILLLS |
| Aeon flux | LSD |
| Afgani indica | Marijuana |
| Afircan bush | Marijuana |
| African | Marijuana |
| African black | Marijuana |
| African salad | Khat |
| African woodbine | Marijuana cigarette |
| Agonies | Withdrawal symptoms |
| Agua | methamphetamine |
| Ah-pen-yen | Opium |
| Aimes | Amyl nitrite |
| Aimies | Amphetamine; amyl nitrite |
| AIP | Heroin from Afganistan, Iran, Pakistan |
| Air blast | Inhalants |
| Airhead | Marijuana user |
| Airplane | Marijuana |
| Al Capone | Heroin |
| Alice B. Toklas | Marijuana brownie |
| alice b. toklas | marijuana |
| All lit up | Under the influence |
| All star | User of multiple drugs |
| All-American drug | Cocaine |
| Alpha-ET | Alpha-ethyltryptamine |
| Ames | Amyl nitrite |
| Amidone | Methadone |
| Amoeba | PCP |
| Amp | Amphetamine; marijuana dipped in embalming fluid, sometimes PCP |
| Amp Head | LSD user |
| Amp Joint | Marijuana cigarette laces w/ some form of narcotic |
| amp joint | marijuana |
| Amped | Using Amphetamine |
| Amped-out | Fatigue after using amphetamine |
| Amping | Accelerated heartbeat |
| AMT | Dimethyltrypamine |
| Amys | Amyl nitrite |
| Anadrol | Oral steroids |
| Anatrofin | Injectable steroids |
| Anavar | Oral steroids |
| Angel | PCP |
| Angel dust | PCP |
| Angel hair | PCP |
| Angel mist | PCP |
| Angel poke | PCP |
| Angie | Cocaine |
| Angola | Marijuana |
| angola | marijuana |
| Animal | LSD |
| Animal trank | PCP |
| Animal tranq | PCP |
| Animal tranquilizer | PCP |
| Antifreeze | Heroin |
| Apache | Fentanyl |
| Apple Jacks | Crack |
| Arctic Blast | Bath Salts |
| Are you anywhere? | Do you use marijuana? |
| Aries | Heroin |
| Arnolds | Steroids |
| Aroma of men | Isobutyl nitrate |
| Around the turn | Having gone through withdrawal period |
| Artillery | Equipment for injecting drugs |
| Ashes | Marijuana |
| Ashes | marijuana |
| Aspirin | Powder cocaine |
| Assassin of Youth | Marijuana |
| Assassin of youth | marijuana |
| Astro turf | Marijuana |
| Atom bomb | Marijuana mixed with heroin |
| Atshitshi | Marijuana |
| Atshitshi | marijuana |
| Atshitshi bomd | marijuana |
| Aunt Hazel | Heroin |
| Aunt Mary | Marijuana |
| aunt mary | marijuana |
| Aunt Nora | Cocaine |
| Aunt,AuntNora | COCAINE/ CRACCK |
| Aunti | Opuim |
| Aunti Emma | Opium |
| Aurora borealis | PCP |
| Author | Doctor who writes illegal prescriptions |